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<i> Verbena littoralis<_i> H.B.K.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (1) Bcl-2 Family (1) Caspase (1) IKK (1) Interleukin Related (1) NF-κB (1) p38 MAPK (1) PI3K (1) Reactive Oxygen Species (1) TNF Receptor (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (1) Neurological Disease (1)

2

Inhibitors & Agonists

2

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

4′-Hydroxywogonin 8-Methoxyapigenin	IKK NF-κB p38 MAPK PI3K Akt Reactive Oxygen Species Interleukin Related TNF Receptor Apoptosis Caspase Bcl-2 Family	Cardiovascular Disease Inflammation/Immunology Cancer
4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis .

Gelsemiol	Others	Neurological Disease
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .

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